James Cook | Medicinal Chemistry | Best Scholar Award

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Prof. James Cook | Medicinal Chemistry | Best Scholar Award

University Distinguished Professor and Adjunct Professor at UNIVERSITY OF WISCONSIN-MILWAUKEE, United States.

James M. Cook πŸ§ͺ is an esteemed scientist and innovator specializing in medicinal chemistry. Based in Milwaukee, WI, he has contributed significantly to drug discovery, particularly in the development of small-molecule treatments for airway hyperresponsiveness and inflammation in asthma. As a key inventor, Cook has collaborated with the UWM Research Foundation to advance intellectual property in pharmaceutical sciences. His research, supported by prestigious grants, has led to groundbreaking advancements in GABA(A) receptor modulators. His dedication to science and innovation continues to shape the future of therapeutic development. πŸŒπŸ”¬

Professional Profile
Suitability for the Best Scholar Award

James M. Cook is a distinguished medicinal chemist πŸ§ͺ with a strong track record of innovative drug discovery and academic excellence. As a professor at the University of Wisconsin-Milwaukee (UWM) πŸ›οΈ, he has significantly contributed to pharmaceutical research, particularly in GABA(A) receptor modulators πŸ’Š for treating neurological and respiratory disorders. His pioneering work has led to multiple patents, high-impact publications, and successful collaborations with the pharmaceutical industry βš•οΈ.

Education πŸŽ“

  • Ph.D. in Medicinal Chemistry – Specialized in drug discovery and organic synthesis πŸ”¬πŸ“š
  • Master’s Degree in Chemistry – Focused on molecular design and pharmaceutical sciences πŸ§ͺ
  • Bachelor’s Degree in Chemistry – Strong foundation in chemical analysis and research πŸ›οΈ

Experience πŸ†

  • Professor at the University of Wisconsin-Milwaukee (UWM) – Leading research in medicinal chemistry πŸ›οΈπŸ‘¨β€πŸ«
  • Principal Investigator in Drug Discovery Projects – Developed novel GABA(A) receptor modulators for treating asthma and neurological disorders πŸ’ŠπŸ”
  • Inventor & Patent Holder – Contributed to multiple patents in pharmaceutical innovation πŸ“œπŸ’‘
  • Recipient of Research Grants – Secured funding from NIH, UWM Research Foundation, and private institutions to advance medical research πŸ’°πŸ§ 
  • Collaborator with Pharmaceutical Industry – Worked with biotech firms to translate research into real-world treatments βš•οΈπŸ­

 

Professional Development πŸš€πŸ“–

James M. Cook has continually advanced his expertise in medicinal chemistry πŸ”¬ through groundbreaking research and innovation. As a professor at the University of Wisconsin-Milwaukee (UWM) πŸ›οΈ, he has mentored young scientists and led pioneering studies on GABA(A) receptor modulators πŸ’Š. His work has earned prestigious research grants πŸ’°, enabling significant contributions to drug discovery. Cook has collaborated with pharmaceutical companies βš•οΈ to translate research into practical treatments. With multiple patents and publications πŸ“œ, he remains committed to scientific excellence. His dedication to innovation, education, and industry partnerships continues to shape modern therapeutics. πŸš€

Research Focus πŸ”πŸ€–

James M. Cook specializes in medicinal chemistry πŸ§ͺ, focusing on the development of GABA(A) receptor modulators for treating neurological and respiratory disorders πŸ§ πŸ’¨. His research explores small-molecule drug design to combat asthma, anxiety, and epilepsy βš•οΈ. With expertise in organic synthesis and pharmaceutical innovation πŸ’‘, he has contributed to groundbreaking treatments targeting airway hyperresponsiveness and inflammation 🌬️. His work integrates biochemical analysis, molecular modeling, and clinical applications πŸ₯. Through academic and industry collaborations 🀝, Cook aims to develop safer and more effective therapeutic agents, enhancing global healthcare solutions. πŸŒπŸ”

Awards & Honors πŸ†

  • Prestigious Research Grants πŸ’° – Funded by NIH, UWM Research Foundation, and private institutions for groundbreaking drug discovery.
  • Patent Holder & Innovator πŸ“œπŸ’‘ – Recognized for multiple patents in medicinal chemistry and pharmaceutical sciences.
  • Distinguished Professor at UWM πŸ›οΈπŸ‘¨β€πŸ« – Honored for excellence in teaching and research contributions.
  • Scientific Contribution Award πŸ§ͺπŸ… – Acknowledged for advancements in GABA(A) receptor modulators.
  • Industry & Academic Collaboration Recognition πŸ€βš•οΈ – Celebrated for translating research into real-world therapeutic applications.
Publication Top Notes:

πŸ“„ Procognitive and neurotrophic benefits of Ξ±5-GABA-A receptor positive allosteric modulation in a Ξ²-amyloid deposition mouse model of Alzheimer’s disease pathology – Neurobiology of Aging, 2025 – πŸ“‘ Cited by: 0

πŸ’Š Intravenous Nanoemulsions Loaded with Phospholipid Complex of a Novel Pyrazoloquinolinone Ligand for Enhanced Brain Delivery – Pharmaceutics, 2025 – πŸ“‘ Cited by: 0

βš•οΈ Antinociceptive Effects of a2/a3-Subtype-Selective GABAA Receptor Positive Allosteric Modulators KRM-II-81 and NS16085 in Male Rats: Behavioral Specificity – Journal of Pharmacology and Experimental Therapeutics, 2024 – πŸ“‘ Cited by: 1

🐡 Evaluation of the sedative-motor effects of novel GABAkine imidazodiazepines using quantitative observation techniques in rhesus monkeys – Journal of Psychopharmacology, 2024 – πŸ“‘ Cited by: 0

🧬 GABA(A) Receptor Activation Drives GABARAP–Nix Mediated Autophagy to Radiation-Sensitize Primary and Brain-Metastatic Lung Adenocarcinoma Tumors – Cancers, 2024 – πŸ“‘ Cited by: 1

🦠 Development of non-sedating benzodiazepines with in vivo antischistosomal activity – Antimicrobial Agents and Chemotherapy, 2024 – πŸ“‘ Cited by: 0

🧠 An alpha 5-GABAA receptor positive allosteric modulator attenuates social and cognitive deficits without changing dopamine system hyperactivity in rats exposed to valproic acid in utero – Autism Research, 2024 – πŸ“‘ Cited by: 0

πŸ”¬ Extrasynaptic Localization Is Essential for Ξ±5GABAA Receptor Modulation of Dopamine System Function – eNeuro, 2024 – πŸ“‘ Cited by: 1

πŸ’‘ New Imidazodiazepine Analogue, 5-(8-Bromo-6-(pyridin-2-yl)-4H-benzo[f]imidazo[1,5-a][1,4]diazepin-3-yl)oxazole, Provides a Simplified Synthetic Scheme, High Oral Plasma and Brain Exposures, and Produces Antiseizure Efficacy in Mice, and Antiepileptogenic Activity in Neural Networks in Brain Slices from a Patient with Mesial Temporal Lobe Epilepsy – ACS Chemical Neuroscience, 2024 – πŸ“‘ Cited by: 2

⚑ KRM–II–81 suppresses epileptiform activity across the neural network of cortical tissue from a patient with pharmacoresistant epilepsy – Heliyon, 2024 – πŸ“‘ Cited by: 2

πŸ“Œ Conclusion:

James M. Cook’s outstanding contributions to medicinal chemistry, intellectual property achievements, and academic leadership make him an exceptional candidate for the Best Scholar Award πŸ†. His dedication to scientific excellence, innovation, and mentorship has significantly impacted modern therapeutics, making him highly deserving of this honor. πŸš€

 

 

 

 

 

 

 

EDUVAN VALENCIA-CRISTANCHO | Rational drug design | Best Researcher Award

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Prof. EDUVAN VALENCIA-CRISTANCHO | Rational drug design | Best Researcher Award

Teacher at Secretary of Education of BogotΓ‘ in Colombia.

Eduvan Daniel Valencia Cristancho πŸ‡¨πŸ‡΄, born on September 26, 1985, in BogotΓ‘, Colombia, is a distinguished chemist specializing in the rational design of compounds with potential antimicrobial activity πŸ§ͺ. He holds a Bachelor’s degree in Chemistry from the Universidad PedagΓ³gica Nacional and a Master’s in Chemical Sciences from the Universidad Nacional de Colombia πŸŽ“. Eduvan has participated as a speaker at national and international conferences on chemistry and science education 🌍. Currently working at the District Education Secretariat, he focuses on computational chemistry and bioinformatics research on NDM-1 inhibitors 🧬, contributing significantly to the country’s scientific and educational advancement πŸ“š.

Professional Profile
Suitability for the Researcher Award

Eduvan is a multidisciplinary researcher whose work addresses global health challenges, especially the fight against antibiotic resistance through the study of NDM-1 inhibitors 🦠. His innovative use of molecular modeling, ADMET analysis, and molecular dynamics has advanced understanding in the search for new antimicrobial compounds πŸ”¬. Additionally, his dedication to merging science, technology, and education through STEAM initiatives πŸŽ¨πŸ“š demonstrates his commitment to both academic excellence and social impact.

EducationΒ πŸŽ“

  • πŸ“˜ Master’s Degree in Chemical Sciences – Universidad Nacional de Colombia (2013 – 2015)
    Research: Rational design of spirothiazolidinone, pyrazolothiazolidinone, and pyrazolo Ξ²-lactam compounds with potential antimicrobial activity.
  • πŸ“— Bachelor’s Degree in Chemistry Education – Universidad PedagΓ³gica Nacional (2004 – 2008)
    Research: Extraction of dextran from orange peel waste and its inclusion in a didactic unit for teaching carbohydrate concepts.
  • πŸ–₯️ Short Course: Microsoft Colombia – Minecraft Education (2021)
  • 🍊 Short Course: Universidad Nacional de Colombia – Aroma Processing for Food (2013)

Experience πŸ’Ό

  • 🏫 Current Position: Educator at the District Education Secretariat of BogotΓ‘
  • 🧠 Researcher:
    • Focus on computational chemistry, bioinformatics, and molecular modeling (NDM-1 inhibitors).
    • Author of several scientific articles and book chapters on molecular docking and antimicrobial compounds.
  • 🎀 Speaker at Events:
    • 9th International Electronic Conference on Medicinal Chemistry (2023)
    • 1st International Congress on Physics Research and Teaching (2022)
    • XXVIII National Physics Congress (2019)
    • 31st Latin American Chemistry Congress (2014)
  • πŸ§ͺ Scientific Contributions:
    • Studies on ADMET properties, molecular dynamics, and micromagnetic simulations.
    • Integration of science and art in education through innovative projects.

 

Professional Development πŸš€πŸ“–

Eduvan Daniel Valencia Cristancho πŸ‡¨πŸ‡΄ has demonstrated continuous professional development through diverse academic and scientific contributions 🧠. He has completed specialized training, such as the Minecraft Education course by Microsoft Colombia (2021) πŸ–₯️ and the Aroma Processing for Food course at Universidad Nacional de Colombia (2013) 🍊. Eduvan actively enhances his expertise in computational chemistry, bioinformatics, and educational innovation πŸ“š. As a frequent speaker at national and international conferences 🌍, he shares his research on molecular modeling and NDM-1 inhibitors 🧬. His commitment to integrating technology, science, and education continues to impact his field profoundly πŸ”¬.

Research Focus πŸ”πŸ€–

Eduvan Daniel Valencia Cristancho πŸ‡¨πŸ‡΄ focuses his research on computational chemistry πŸ§ͺ, bioinformatics πŸ’», and molecular modeling 🧬, particularly targeting NDM-1 enzyme inhibitors to combat antimicrobial resistance 🦠. His work involves in silico studies, including ADMET analysis, molecular docking, and molecular dynamics simulations πŸ”. Additionally, he contributes to organic chemistry through the rational design of bioactive compounds 🌿. Eduvan also integrates STEAM education πŸŽ¨πŸ“š, exploring the connection between science and art to create innovative learning experiences for students 🏫. His interdisciplinary approach strengthens both scientific research and educational methodologies worldwide 🌍.

Awards & Honors πŸ…πŸŽ–οΈ
  • 🎀 Recognized speaker at prestigious national and international scientific events, such as:
    • 9th International Electronic Conference on Medicinal Chemistry (2023) 🌍
    • 1st International Congress on Physics Research and Teaching (2022) 🧠
    • XXVIII National Physics Congress (2019) πŸ”¬
    • 31st Latin American Chemistry Congress (2014) 🌎
  • πŸ“š Contributor to peer-reviewed scientific journals with impactful publications on NDM-1 inhibitors and computational chemistry 🧬.
  • 🎨 Acknowledged for integrating art and science in innovative educational projects through STEAM education initiatives 🏫.

 

Publication Top Notes:

“Review, Characterization, and Bioinformatic Analysis of New Delhi Metallo-Ξ²-Lactamase-1 (NDM-1)” – Published in Revista de la Facultad de Ciencias (2023) πŸ“… | πŸ“‘ Cited by: Not specified

πŸ“„ “In Silico Study of the ADMET Properties of Potential Inhibitors of New Delhi Metallo-Ξ²-Lactamase-1 (NDM-1)” – Published in Development of the International Agricultural Commerce Since the Mid Seventies (2023) πŸ“… | πŸ“‘ Cited by: Not specified

πŸ“„ “Estimation of Bond Free Energy with Gmx_Mmpbsa in NDM-1 Complexes” – Published in Advanced Journal of Chemistry Section A (2024) πŸ“… | πŸ“‘ Cited by: Not specified

πŸ“„ “In Silico Evaluation of Potential NDM-1 Inhibitors: An Integrated Docking and Molecular Dynamics Approach” – Published in Pharmaceuticals (2024) πŸ“… | πŸ“‘ Cited by: Not specified

πŸ“• Book Chapter: “In Silico Study of the ADMET Properties of Potential Inhibitors of NDM-1” in Uniting Knowledge Integrated Scientific Research for Global Development (2023) πŸ“…

πŸ“• Book Chapter: “Science and Art ‘Transformer of Lives'” in Education of the Future: Inspiration Through Innovative Experiences DOKUMA 2022 (2023) πŸ“…

πŸ“Œ Conclusion:

With a strong track record of innovative research, impactful publications, and contributions to scientific education, Eduvan Daniel Valencia Cristancho is an excellent candidate for the Best Researcher Award πŸ…. His work not only advances critical fields like antimicrobial resistance research but also bridges the gap between science and education, making lasting contributions to both the scientific community and society at large 🌟.