Maria TIRITAN | Organic Chemistry | Best Paper Award

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Prof. Maria TIRITAN | Organic Chemistry | Best Paper Award

Professor at Faculdade de FarmΓ‘cia da Universidade do Porto in Portugal.

Maria Elizabeth Tiritan πŸŽ“πŸ”¬ is a distinguished researcher at CIIMAR and an Assistant Professor of Organic Chemistry and Pharmaceutical Sciences at the University of Porto πŸ‡΅πŸ‡Ή. With a PhD in Organic Chemistry, she has led groundbreaking studies in chiral pharmaceuticals, environmental toxicology πŸŒ±πŸ’Š, and green drug development. A pioneer in enantioselective biodegradation, she has authored over 130 publications, holds two patents πŸ“šπŸ§ͺ, and has an h-index of 39. Passionate about sustainable science, she coordinates multiple international projects 🌍 and mentors emerging scientists, fostering innovation in medicinal and environmental chemistry πŸŒΏπŸ‘©β€πŸ”¬.

Professional Profile

GOOGLE SCHOLAR

πŸ” Summary of Suitability:

This paper showcases Maria Elizabeth Tiritan’s deep expertise in organic and medicinal chemistry, highlighting the importance of chirality in flavonoidsβ€”a class of compounds with significant pharmacological activity πŸ’ŠπŸŒΏ. The work offers a comprehensive overview of stereoselective synthesis methods, combining fundamental chemistry with applied biomedical relevance. It underscores how stereochemistry affects biological function, paving the way for safer and more effective drug candidates πŸ”πŸ”„.

πŸŽ“ Education

  • πŸ§ͺ PhD in Organic Chemistry – University of Porto, Portugal (1996)
    Thesis: Enantiomeric Resolution of Chiral Sulfoxides by HPLC

  • πŸ“š Postdoctoral Research – Organic Chemistry (1997–2001)
    Faculty of Pharmacy, University of Porto

  • 🌍 Visiting Researcher – University of Warwick, UK (1992–1995)
    Under WHO and CNPq (Brazil) programs

  • πŸŽ“ Degree in Chemistry – Brazil (before 1992)

πŸ’Ό Experience

  • πŸ‘©β€πŸ« Assistant Professor – Faculty of Pharmacy, University of Porto (2020–Present)

  • 🧫 Researcher – CIIMAR, University of Porto (2015–2018, 2022–Present)

  • 🧬 Team Leader – Drug Research Line at IINFACTS (2018–2021)

  • 🌱 Coordinator – Environmental Research Unit, IINFACTS (2013–2017)

  • πŸ§ͺ Group Leader – Chemical & Pharmaceutical Sciences at CESPU (2007–2012)

  • πŸ§‘β€πŸ”¬ Postdoctoral Fellow – Faculty of Pharmacy, University of Porto (1997–2001)

  • 🌐 Research Collaborator – Multiple international and national projects focused on chiral drugs, environmental pollutants, and green chemistry

Professional Development πŸš€πŸ“–

Maria Elizabeth Tiritan has demonstrated remarkable professional development through a dynamic career in research and academia πŸ“šπŸ”¬. From her early work as a visiting researcher at the University of Warwick 🌍 to her postdoctoral studies in organic chemistry at the University of Porto πŸ§ͺ, she has steadily advanced as a leading scientist in medicinal and environmental chemistry πŸŒΏπŸ’Š. She became a group leader, team coordinator, and principal investigator on several innovative projects, particularly in green pharmaceuticals and enantioselective analysis πŸ”„πŸŒ±. As an Assistant Professor and project leader, she continues mentoring students and shaping sustainable scientific research πŸŒŽπŸ‘©β€πŸ«

Research Focus πŸ”πŸ€–

Maria Elizabeth Tiritan’s research focuses on Organic Chemistry, Medicinal Chemistry, and Environmental Sciences πŸ§ͺπŸ’ŠπŸŒ±. Her work is centered on chirality, enantioselective analysis, and the development of eco-friendly pharmaceuticals πŸŒπŸ”„. She investigates how chiral drugs behave in biological and environmental systems, aiming to design safer, biodegradable compounds β™»οΈπŸ§¬. A key part of her research also includes separating enantiomers using liquid chromatography and membranes πŸ”¬πŸ’‘. Her studies contribute to both public health and environmental protection, linking chemistry with sustainable development goals 🌿🌐. Through innovation and green chemistry, she leads efforts to reduce pharmaceutical pollution in ecosystems πŸŒŠβš—οΈ.

Awards and Honors πŸ†πŸŽ–οΈ

  • 🧠 Principal Investigator of 8 funded projects at CESPU – Recognized leadership in innovative pharmaceutical and environmental research πŸŽ―πŸ’Š

  • πŸ“˜ Editor & Author of major scientific books and chapters – Including Chiral Separations and Stereochemical Elucidation published by Wiley πŸ“šβœοΈ

  • πŸ”¬ Reviewer & Committee Member – Evaluator for international research fellowships and grant applications, including ERC Starting Grant πŸ§ͺ🌍

  • πŸ’Ό Coordinator of Sustainable Development Goals Working Group at FFUP since 2021 – For advancing eco-conscious research goals 🌿🧭

  • πŸ“ˆ 131 publications with 4019 citations and an h-index of 39 – Recognition for impactful scientific contributions πŸ“ŠπŸ…

Publications & Citations πŸ“š

  • Organic Chemistry – LG Wade πŸ“˜ Pearson Education India, 2008 – 1718 citations

  • Performance of aerobic granular sludge… – CL Amorim et al. πŸ’Š Water Research, 2014 – 257 citations

  • Biodegradation of ofloxacin, norfloxacin, and ciprofloxacin… – CL Amorim et al. πŸ§ͺ Applied Microbiology and Biotechnology, 2014 – 221 citations

  • Monitoring of the 17 EU Watch List contaminants… – JCG Sousa et al. 🌍 Science of the Total Environment, 2019 – 214 citations

  • Spatiotemporal distribution of pharmaceuticals… – TV Madureira et al. 🌊 Science of the Total Environment, 2010 – 201 citations

  • Chiral stationary phases for liquid chromatography… – J Teixeira et al. πŸ”¬ Molecules, 2019 – 172 citations

  • Seasonal and spatial distribution of endocrine-disrupting compounds… – C Ribeiro et al. 🌱 Archives of Environmental Contamination and Toxicology, 2009 – 139 citations

  • Enrichment of bacterial strains for the biodegradation… – VS Bessa et al. 🧫 International Biodeterioration & Biodegradation, 2017 – 134 citations

  • Degradation of fluoroquinolone antibiotics… – AS Maia et al. πŸ’‰ Journal of Chromatography A, 2014 – 133 citations

  • Enantioseparation of chiral pharmaceuticals… – AR Ribeiro et al. βš–οΈ Journal of Chromatography B, 2014 – 130 citations

  • Enantioselectivity in drug pharmacokinetics and toxicity… – MM Coelho et al. πŸ’Š Molecules, 2021 – 125 citations

  • New trends in sample preparation techniques… – C Ribeiro et al. 🧴 Critical Reviews in Analytical Chemistry, 2014 – 121 citations

  • Chiral pharmaceuticals in the environment – AR Ribeiro et al. 🌐 Environmental Chemistry Letters, 2012 – 104 citations

Β πŸ” Conclusion:

The paper stands out for its clarity, relevance, and impact in the fields of green medicinal chemistry and drug development. Given its scientific merit, innovation, and interdisciplinary value, it is a strong contender for the Best Paper Award πŸ₯‡πŸ“–.

 

 

James Cook | Medicinal Chemistry | Best Scholar Award

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Prof. James Cook | Medicinal Chemistry | Best Scholar Award

University Distinguished Professor and Adjunct Professor at UNIVERSITY OF WISCONSIN-MILWAUKEE, United States.

James M. Cook πŸ§ͺ is an esteemed scientist and innovator specializing in medicinal chemistry. Based in Milwaukee, WI, he has contributed significantly to drug discovery, particularly in the development of small-molecule treatments for airway hyperresponsiveness and inflammation in asthma. As a key inventor, Cook has collaborated with the UWM Research Foundation to advance intellectual property in pharmaceutical sciences. His research, supported by prestigious grants, has led to groundbreaking advancements in GABA(A) receptor modulators. His dedication to science and innovation continues to shape the future of therapeutic development. πŸŒπŸ”¬

Professional Profile
Suitability for the Best Scholar Award

James M. Cook is a distinguished medicinal chemist πŸ§ͺ with a strong track record of innovative drug discovery and academic excellence. As a professor at the University of Wisconsin-Milwaukee (UWM) πŸ›οΈ, he has significantly contributed to pharmaceutical research, particularly in GABA(A) receptor modulators πŸ’Š for treating neurological and respiratory disorders. His pioneering work has led to multiple patents, high-impact publications, and successful collaborations with the pharmaceutical industry βš•οΈ.

Education πŸŽ“

  • Ph.D. in Medicinal Chemistry – Specialized in drug discovery and organic synthesis πŸ”¬πŸ“š
  • Master’s Degree in Chemistry – Focused on molecular design and pharmaceutical sciences πŸ§ͺ
  • Bachelor’s Degree in Chemistry – Strong foundation in chemical analysis and research πŸ›οΈ

Experience πŸ†

  • Professor at the University of Wisconsin-Milwaukee (UWM) – Leading research in medicinal chemistry πŸ›οΈπŸ‘¨β€πŸ«
  • Principal Investigator in Drug Discovery Projects – Developed novel GABA(A) receptor modulators for treating asthma and neurological disorders πŸ’ŠπŸ”
  • Inventor & Patent Holder – Contributed to multiple patents in pharmaceutical innovation πŸ“œπŸ’‘
  • Recipient of Research Grants – Secured funding from NIH, UWM Research Foundation, and private institutions to advance medical research πŸ’°πŸ§ 
  • Collaborator with Pharmaceutical Industry – Worked with biotech firms to translate research into real-world treatments βš•οΈπŸ­

 

Professional Development πŸš€πŸ“–

James M. Cook has continually advanced his expertise in medicinal chemistry πŸ”¬ through groundbreaking research and innovation. As a professor at the University of Wisconsin-Milwaukee (UWM) πŸ›οΈ, he has mentored young scientists and led pioneering studies on GABA(A) receptor modulators πŸ’Š. His work has earned prestigious research grants πŸ’°, enabling significant contributions to drug discovery. Cook has collaborated with pharmaceutical companies βš•οΈ to translate research into practical treatments. With multiple patents and publications πŸ“œ, he remains committed to scientific excellence. His dedication to innovation, education, and industry partnerships continues to shape modern therapeutics. πŸš€

Research Focus πŸ”πŸ€–

James M. Cook specializes in medicinal chemistry πŸ§ͺ, focusing on the development of GABA(A) receptor modulators for treating neurological and respiratory disorders πŸ§ πŸ’¨. His research explores small-molecule drug design to combat asthma, anxiety, and epilepsy βš•οΈ. With expertise in organic synthesis and pharmaceutical innovation πŸ’‘, he has contributed to groundbreaking treatments targeting airway hyperresponsiveness and inflammation 🌬️. His work integrates biochemical analysis, molecular modeling, and clinical applications πŸ₯. Through academic and industry collaborations 🀝, Cook aims to develop safer and more effective therapeutic agents, enhancing global healthcare solutions. πŸŒπŸ”

Awards & Honors πŸ†

  • Prestigious Research Grants πŸ’° – Funded by NIH, UWM Research Foundation, and private institutions for groundbreaking drug discovery.
  • Patent Holder & Innovator πŸ“œπŸ’‘ – Recognized for multiple patents in medicinal chemistry and pharmaceutical sciences.
  • Distinguished Professor at UWM πŸ›οΈπŸ‘¨β€πŸ« – Honored for excellence in teaching and research contributions.
  • Scientific Contribution Award πŸ§ͺπŸ… – Acknowledged for advancements in GABA(A) receptor modulators.
  • Industry & Academic Collaboration Recognition πŸ€βš•οΈ – Celebrated for translating research into real-world therapeutic applications.
Publication Top Notes:

πŸ“„ Procognitive and neurotrophic benefits of Ξ±5-GABA-A receptor positive allosteric modulation in a Ξ²-amyloid deposition mouse model of Alzheimer’s disease pathology – Neurobiology of Aging, 2025 – πŸ“‘ Cited by: 0

πŸ’Š Intravenous Nanoemulsions Loaded with Phospholipid Complex of a Novel Pyrazoloquinolinone Ligand for Enhanced Brain Delivery – Pharmaceutics, 2025 – πŸ“‘ Cited by: 0

βš•οΈ Antinociceptive Effects of a2/a3-Subtype-Selective GABAA Receptor Positive Allosteric Modulators KRM-II-81 and NS16085 in Male Rats: Behavioral Specificity – Journal of Pharmacology and Experimental Therapeutics, 2024 – πŸ“‘ Cited by: 1

🐡 Evaluation of the sedative-motor effects of novel GABAkine imidazodiazepines using quantitative observation techniques in rhesus monkeys – Journal of Psychopharmacology, 2024 – πŸ“‘ Cited by: 0

🧬 GABA(A) Receptor Activation Drives GABARAP–Nix Mediated Autophagy to Radiation-Sensitize Primary and Brain-Metastatic Lung Adenocarcinoma Tumors – Cancers, 2024 – πŸ“‘ Cited by: 1

🦠 Development of non-sedating benzodiazepines with in vivo antischistosomal activity – Antimicrobial Agents and Chemotherapy, 2024 – πŸ“‘ Cited by: 0

🧠 An alpha 5-GABAA receptor positive allosteric modulator attenuates social and cognitive deficits without changing dopamine system hyperactivity in rats exposed to valproic acid in utero – Autism Research, 2024 – πŸ“‘ Cited by: 0

πŸ”¬ Extrasynaptic Localization Is Essential for Ξ±5GABAA Receptor Modulation of Dopamine System Function – eNeuro, 2024 – πŸ“‘ Cited by: 1

πŸ’‘ New Imidazodiazepine Analogue, 5-(8-Bromo-6-(pyridin-2-yl)-4H-benzo[f]imidazo[1,5-a][1,4]diazepin-3-yl)oxazole, Provides a Simplified Synthetic Scheme, High Oral Plasma and Brain Exposures, and Produces Antiseizure Efficacy in Mice, and Antiepileptogenic Activity in Neural Networks in Brain Slices from a Patient with Mesial Temporal Lobe Epilepsy – ACS Chemical Neuroscience, 2024 – πŸ“‘ Cited by: 2

⚑ KRM–II–81 suppresses epileptiform activity across the neural network of cortical tissue from a patient with pharmacoresistant epilepsy – Heliyon, 2024 – πŸ“‘ Cited by: 2

πŸ“Œ Conclusion:

James M. Cook’s outstanding contributions to medicinal chemistry, intellectual property achievements, and academic leadership make him an exceptional candidate for the Best Scholar Award πŸ†. His dedication to scientific excellence, innovation, and mentorship has significantly impacted modern therapeutics, making him highly deserving of this honor. πŸš€